|
| 產(chǎn)地 | 進(jìn)口、國(guó)產(chǎn) |
| 品牌 | 上海莼試 |
| 保存條件 | Store at -20 °C |
| 貨號(hào) | CS11618 |
| 應(yīng)用范圍 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS編號(hào) | |
| 抗體名 | Anti-TFIID/TATA binding protein TBP |
| 克隆性 | |
| 靶點(diǎn) | 詳見(jiàn)說(shuō)明書(shū) |
| 適應(yīng)物種 | 詳見(jiàn)說(shuō)明書(shū) |
| 形態(tài) | 詳見(jiàn)說(shuō)明書(shū) |
| 宿主 | 詳見(jiàn)說(shuō)明書(shū) |
| 亞型 | IgG |
| 標(biāo)識(shí)物 | 詳見(jiàn)說(shuō)明書(shū) |
| 濃度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human TATA binding protein TBP |
全、新、優(yōu)、品、好四大特點(diǎn)：
TATA結(jié)合蛋白TBP抗體規(guī)格 全：公司提供上萬(wàn)種產(chǎn)品，涵蓋了生物試劑，elisa試劑盒，標(biāo)準(zhǔn)品，培養(yǎng)基，原裝耗材，抗體、培養(yǎng)基、ATCC細(xì)胞等，基本上各種科研所需產(chǎn)品在我司都能找到。
新：產(chǎn)品更新速度較快，基本上每周都有新產(chǎn)品出現(xiàn)。
優(yōu)：產(chǎn)品質(zhì)量好，投訴比較少。
好：我公司具有優(yōu)質(zhì)的技術(shù)團(tuán)隊(duì)，產(chǎn)品一旦售出，實(shí)驗(yàn)過(guò)程中遇到困難可提供在線技術(shù)咨詢(xún)。使您使用產(chǎn)品時(shí)沒(méi)有任何的后顧之憂(yōu)。
TATA結(jié)合蛋白TBP抗體規(guī)格 英文名稱(chēng) Anti-TFIID/TATA binding protein TBP
中文名稱(chēng) TATA結(jié)合蛋白TBP抗體規(guī)格
別 名 GTF2D; GTF2D1; MGC117320; MGC126054; MGC126055; SCA 17; SCA17; TATA binding factor; TATA box binding protein; TATA box factor; TATA sequence binding protein; TATA sequence-binding protein; TATA-binding factor; TATA-box factor; TATA-box-binding protein; TBP; TBP_HUMAN; TF2D; TFIID; Transcription initiation factor TFIID TBP subunit.
產(chǎn)品屬性：
濃 度 1mg/1ml
規(guī) 格 0.2ml/200μg
抗體來(lái)源 Rabbit
克隆類(lèi)型 polyclonal
交叉反應(yīng) Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
產(chǎn)品類(lèi)型 一抗
研究領(lǐng)域 細(xì)胞生物 神經(jīng)生物學(xué) 干細(xì)胞 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué)
蛋白分子量 predicted molecular weight: 38kDa
性 狀 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human TATA binding protein TBP
亞 型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
TATA結(jié)合蛋白TBP抗體規(guī)格 產(chǎn)品應(yīng)用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500
（石蠟切片需做抗原修復(fù)）
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
產(chǎn)品介紹 In eukaryotic systems, initiation of transcription from protein-coding genes is a complex process requiring RNA polymerase II and broad families of auxiliary transcription factors. Such factors can be divided into two major functional classes: the basal factors that are required for transcription of all Pol II genes, including TFIIA, TFIIB, TFIID, TFIIE, TFIIF and TFIIH; and sequence-specific factors that regulate gene expression. The basal transcription factors and Pol II form a specific multiprotein complex near the transcription start site by interacting with core promotor elements such as the TATA box generally located 25-30 base pairs upstream of the transcription start site. Binding of TFIID to the TATA element initiates assembly of the other factors into a pre-initiation complex. The TATA-binding subunit of TFIID (designated TFIIDt or TBP) from higher eukaryotes contains a highly conserved 180 amino acid C-terminal domain.
Function : General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Subunit : Binds DNA as monomer. Belongs to the TFIID complex together with the TBP-associated factors (TAFs). Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B TAF1C and TAF1D. Association of TBP to form either TFIID or SL1/TIF-IB appears to be mutually exclusive. Interacts with TAF1A, TAF1B and TAF1C. Interacts with TFIIB, NCOA6, DRAP1, DR1 and ELF3. Interacts with SPIB, SNAPC1, SNAPC2 and SNAPC4. Interacts with UTF1. Interacts with BRF2. Interacts with UBTF. Interacts with GPBP1. Interacts with CITED2 (By similarity). Interacts with ATF7IP. Interacts with -1 Tat.
Subcellular Location : Nucleus.
Tissue Specificity : Widely expressed, with levels highest in the testis and ovary.
DISEASE : Defects in TBP are the cause of spinocerebellar ataxia type 17 (SCA17) [MIM:607136]. Spinocerebellar ataxia is a clinically and genetically heterogeneous group of cerebellar disorders. Patients show progressive incoordination of gait and often poor coordination of hands, speech and eye movements, due to degeneration of the cerebellum with variable involvement of the brainstem and spinal cord. SCA17 is an autosomal dominant cerebellar ataxia (ADCA) characterized by widespread cerebral and cerebellar atrophy, dementia and extrapyramidal signs. The molecular defect in SCA17 is the expansion of a CAG repeat in the coding region of TBP. Longer expansions result in earlier onset and more severe clinical manifestations of the disease.
Similarity : Belongs to the TBP family.
Database links : UniProtKB/Swiss-Prot: P20226.2
實(shí)驗(yàn)流程：
正在熱銷(xiāo)的相關(guān)產(chǎn)品：
FGF4/HSTF1/HBGF-4(Fibroblast Growth Factor4) 纖維母細(xì)胞生長(zhǎng)因子4抗原Multi-class antibodies規(guī)格： 0.5mg
腦素/利肽抗體 Anti-BNP 0.1ml
Rhesus antibody Rh phospho-E2F1 (Ser332) 磷酸化轉(zhuǎn)錄因子E2F-1抗體 規(guī)格 0.1ml
纖維素膜(30cm×3m 0.45um) 1卷 Whatman
ZNF281 英文名稱(chēng)： 鋅指蛋白281抗體 0.2ml
DEF6/IBP 英文名稱(chēng)： 干擾素調(diào)節(jié)因子4結(jié)合蛋白抗體 0.2ml
腦素/利肽抗體 Anti-BNP 0.1ml
Ezrin/Radixin 埃茲蛋白(多肽)Multi-class antibodies規(guī)格： 0.5mg
丁酰膽堿脂酶抗體(N端) Anti-BCHENT 0.1ml
Rhesus antibody Rh phospho-EGFR (Ser1142) 磷酸化表皮生長(zhǎng)因子受體抗體 規(guī)格 0.1ml
馬血清 100ml Gibco
ZNF772 英文名稱(chēng)： 鋅指蛋白772抗體 0.2ml
DOK1 英文名稱(chēng)： D酪酸激酶衰減蛋白1抗體 0.1ml
丁酰膽堿脂酶抗體(N端) Anti-BCHENT 0.1ml
PROG ELISA kit 大鼠孕激素/孕酮Multi-class antibodies規(guī)格： 48T
Anti-ARHI/FITC 熒光素標(biāo)記ARHI蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
Rhesus antibody Rh FAM13B1 FAM13B1蛋白抗體 規(guī)格 0.2ml
CaN ELISA Kit 大鼠鈣調(diào)磷酸酶 96T
5 MethylCytosine 英文名稱(chēng)： 5甲基胞嘧啶抗體 0.1ml
phospho-Androgen Receptor (Ser791) 英文名稱(chēng)： 磷酸化雄激素受體抗體 0.1ml
Anti-ARHI/FITC 熒光素標(biāo)記ARHI蛋白抗體IgGMulti-class antibodies規(guī)格： 0.2ml
人補(bǔ)體調(diào)節(jié)蛋白(CCP)ELISA 試劑盒 96T/48T 試劑盒 組裝/原裝
豚鼠催產(chǎn)素(OT)免疫試劑盒 Guinea Pig Oxytocin,OT ELISA Kit
髓樣分化因子初次應(yīng)答基因88(MYD88)ELISA試劑盒 ，英文名： MYD88 ELISA Kit
MouseUlasensitivityThyroxine,u-T4ELISA試劑盒小鼠高敏甲狀腺素(u-T4)ELISA試劑盒規(guī)格：96T/48T
Elisa藍(lán)耳病檢測(cè)試劑盒5*96孔5*96孔
HumanAngiotensinⅡReceptor2,AT2RELISAKit人緊張素Ⅱ受體2(AT2R)ELISA試劑盒規(guī)格：96T/48T
大鼠脫氫表雄酮(DHEA)ELISA試劑盒 ，英文名： DHEA ELISA Kit
人癌標(biāo)志物-CA153ELISA檢測(cè)試劑盒HumanmammarycarcinomaMarker-CA153ELISAKit 96T/48T
倉(cāng)鼠谷胱甘肽過(guò)氧化物酶3(GPX3)免疫試劑盒 Hamster glathione peroxidase 3,GPX3 ELISA kit
CLIAKitforPV-IgG(HumanPoliomyelitisVirus)ELISAKit人病毒IgG規(guī)格：48T/96T
石蠟切片脂質(zhì)尼羅紅間接染色試劑盒50次
ELISAKitOPG人骨保護(hù)素規(guī)格：48T/96T
TATA結(jié)合蛋白TBP抗體規(guī)格 大鼠線粒體解偶聯(lián)蛋白1(UCP1)ELISA試劑盒 ，英文名： UCP1 ELISA Kit
Pla vitamin E (VE) ELISA Kit 植物維生素E(VE)ELISA試劑盒
MouseImmunoglobulinE,IgEELISAKit 小鼠免疫球蛋白E(IgE)ELISA試劑盒 96T/48T 進(jìn)口分裝
CLIAKitforHumanalpha-granularmembraneprotein,GMP-140ELISAKit人血漿α顆粒膜蛋白規(guī)格：48T/96T
細(xì)胞HHV6(HUMANHERPESVIRUS6)病毒定性檢測(cè)試劑盒20次
ELISAKitSOD大鼠超氧化物歧化酶規(guī)格：48T/96T
技術(shù)外包服務(wù):
★TATA結(jié)合蛋白TBP抗體規(guī)格 分子生物學(xué)：質(zhì)粒抽提、PCR、Q-PCR、RT-PCR、分子生物學(xué)：基因合成、引物合成、基因測(cè)序、載體構(gòu)建等
★蛋白工程：原核、哺乳動(dòng)物蛋白表達(dá)系統(tǒng)等
★病毒包裝：腺病毒、慢病毒等
★抗體工程：磁珠分選、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等
★細(xì)胞工程：細(xì)胞表型分析(凋亡、增殖、周期、遷移、侵襲、修復(fù)、克隆形成)、細(xì)胞培養(yǎng)、細(xì)胞膜制備、穩(wěn)定細(xì)胞株構(gòu)建、細(xì)胞RNAi技術(shù)等等。
|
|
|
|
|
